{"id":237468,"date":"2022-01-12T16:36:24","date_gmt":"2022-01-12T21:36:24","guid":{"rendered":"https:\/\/ziliahealth.com\/blog\/ocular-oximetry-paradigm-shift-in-retinal-vein-occlusion-management\/"},"modified":"2022-01-12T17:29:52","modified_gmt":"2022-01-12T22:29:52","slug":"oxymetrie-oculaire-changement-paradigme-gestion-occlusions-veineuses-retiniennes","status":"publish","type":"post","link":"https:\/\/ziliahealth.com\/fr\/blog\/oxymetrie-oculaire-changement-paradigme-gestion-occlusions-veineuses-retiniennes\/","title":{"rendered":"Oxym\u00e9trie oculaire : Un changement de paradigme dans la gestion des occlusions veineuses r\u00e9tiniennes?"},"content":{"rendered":"

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des occlusions veineuses r\u00e9tiniennes?\u00a0\u00bb button_url=\u00a0\u00bbhttps:\/\/jhvs2020.jp\/en\/\u00a0\u00bb url_new_window=\u00a0\u00bbon\u00a0\u00bb admin_label=\u00a0\u00bbTitle Paragraph & CTA Button\u00a0\u00bb _builder_version=\u00a0\u00bb4.14.5″ header_font=\u00a0\u00bbMontserrat|500|||||||\u00a0\u00bb header_text_color=\u00a0\u00bb#5A5A5A\u00a0\u00bb header_font_size=\u00a0\u00bb3rem\u00a0\u00bb header_line_height=\u00a0\u00bb1.2em\u00a0\u00bb body_font=\u00a0\u00bbMontserrat Regular||||||||\u00a0\u00bb body_text_color=\u00a0\u00bb#5A5A5A\u00a0\u00bb body_font_size=\u00a0\u00bb1.1rem\u00a0\u00bb body_line_height=\u00a0\u00bb1.6em\u00a0\u00bb use_background_color=\u00a0\u00bboff\u00a0\u00bb custom_button=\u00a0\u00bbon\u00a0\u00bb button_text_size=\u00a0\u00bb1rem\u00a0\u00bb button_text_color=\u00a0\u00bb#5a5a5a\u00a0\u00bb button_border_width=\u00a0\u00bb0px\u00a0\u00bb button_border_color=\u00a0\u00bbrgba(0,0,0,0)\u00a0\u00bb 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L’occlusion veineuse r\u00e9tinienne (OVR) touche plus de 1,1 million de personnes aux \u00c9tats-Unis et est consid\u00e9r\u00e9e comme l\u2019une des principales causes de perte de vision chez les personnes \u00e2g\u00e9es. <\/span>(1)<\/p>\n

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Il existe deux types d\u2019OVR selon la localisation de l’obstruction: occlusion de la veine centrale de la r\u00e9tine (OVCR) et occlusion d\u2019une branche veineuse de la r\u00e9tine (OBVR). (2) <\/span>L’OVCR se produit lorsqu’il y a une obstruction de la veine r\u00e9tinienne principale en arri\u00e8re de la lame cribl\u00e9e du nerf optique et est typiquement le r\u00e9sultat d’une thrombose. L\u2019OVCR peut \u00eatre subdivis\u00e9e en deux cat\u00e9gories : isch\u00e9mique (non perfus\u00e9e) et non isch\u00e9mique (perfus\u00e9e). Environ 70 % des cas sont non isch\u00e9miques et se caract\u00e9risent par une acuit\u00e9 visuelle relativement bonne (sup\u00e9rieure \u00e0 20\/200), un d\u00e9faut pupillaire aff\u00e9rent faible ou absent et des changements visuels l\u00e9gers. Les 30 % de cas restants sont isch\u00e9miques, se manifestent par une non-perfusion capillaire r\u00e9tinienne d’au moins 10 diam\u00e8tres de disque et pr\u00e9sentent g\u00e9n\u00e9ralement un mauvais pronostic visuel. (2) L’hypoxie qui en r\u00e9sulte peut augmenter le facteur de croissance de l\u2019endoth\u00e9lium vasculaire (VEGF), induisant \u0153d\u00e8me maculaire et\/ou n\u00e9ovascularisation de l’iris ou de la r\u00e9tine. (3)<\/span><\/p>\n

L\u2019OBVR, quant \u00e0 elle, est une occlusion survenant dans l\u2019une des branches de la veine centrale de la r\u00e9tine. (2) Le sympt\u00f4me le plus courant de l\u2019OBVR est une vision floue ou une perte de vision dans une partie de l\u2019oeil. Elle peut survenir soudainement ou se d\u00e9velopper progressivement sur plusieurs heures ou jours.<\/span><\/p>\n

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Physiopathologie, \u00e9pid\u00e9miologie et facteurs de risque<\/h3>\n

La pr\u00e9valence globale de l\u2019OVR chez les personnes \u00e2g\u00e9es de 30 \u00e0 89 ans \u00e9tait estim\u00e9e en 2015 \u00e0 28 millions de personnes. (5) L’\u00e2ge est un facteur de risque important pour le d\u00e9veloppement de l’OVR avec 90 % des patients atteints ayant plus de 50 ans. (2) Les autres facteurs de risque sont le glaucome, les drusens et l’\u0153d\u00e8me papillaire, l’\u00e9tat d’hypercoagulation, la syphilis, la sarco\u00efdose, la race afro-am\u00e9ricaine, la dr\u00e9panocytose, le virus de l’immunod\u00e9ficience humaine (VIH), la vascularite, la prise de certains m\u00e9dicaments tels les contraceptifs oraux et les diur\u00e9tiques, les troubles de la fonction plaquettaire, une maladie orbitaire et, rarement, les migraines. (2)<\/p>\n

La thrombose \u00e9tant la principale cause de l’OVR, les conditions m\u00e9dicales entra\u00eenant une augmentation des \u00e9l\u00e9ments contribuant \u00e0 la thrombose, comme la stase veineuse, les l\u00e9sions endoth\u00e9liales ou l’hypercoagulabilit\u00e9, pourraient entra\u00eener une OVR. (2) Enfin, les habitudes de vie telles que la consommation d’alcool et le tabagisme peuvent \u00e9galement avoir un impact direct sur l’OVR car elles contribuent \u00e0 l’hypertension, au diab\u00e8te et \u00e0 l’hyperlipid\u00e9mie, qui sont tous des facteurs de risque connus de maladies vasculaires r\u00e9tiniennes. (4)<\/p>\n

Diagnostic<\/h3>\n

Le diagnostic de l’OVR se fait principalement par un examen oculaire approfondi qui comprend une \u00e9valuation du fond d’\u0153il sous dilatation. Une fois la dysfonction vasculaire constat\u00e9e, la photographie du fond d’\u0153il peut \u00eatre utilis\u00e9e \u00e0 des fins d\u2019\u00e9ducation du patient et pour suivre l\u2019\u00e9volution de la maladie au fil du temps. La tomographie par coh\u00e9rence optique (OCT) est \u00e9galement utile pour v\u00e9rifier la pr\u00e9sence ou l’absence d’un \u0153d\u00e8me maculaire, ce qui peut influer sur la prise en charge de l’affection. L’angiographie \u00e0 la fluoresc\u00e9ine (AF) est une approche plus invasive pouvant \u00eatre utilis\u00e9e pour d\u00e9terminer l’\u00e9tat de perfusion de la r\u00e9tine et \u00e9valuer de mani\u00e8re qualitative la d\u00e9ficience en oxyg\u00e9nation dans les tissus. L’av\u00e8nement de l’angiographie par tomographie \u00e0 coh\u00e9rence optique (OCT-A) offre un moyen alternatif et non invasif d’imager les r\u00e9seaux capillaires r\u00e9tiniens profonds et superficiels. En fait, cette technologie s\u2019est av\u00e9r\u00e9e plus efficace que l’AF pour visualiser et analyser le r\u00e9seau capillaire de la macula, ainsi que pour d\u00e9tecter les \u0153d\u00e8mes maculaires. (6) Malheureusement, cette technologie n’est pas sans limitations, car l’OCT-A est sujet \u00e0 divers artefacts tels que des artefacts d’ombrage associ\u00e9s \u00e0 une h\u00e9morragie intrar\u00e9tinienne\/sous-r\u00e9tinienne, des artefacts de projection des vaisseaux r\u00e9tiniens superficiels sur les couches r\u00e9tiniennes plus profondes et des artefacts li\u00e9s au mouvement. (12)<\/p>\n

Traitement<\/h3>\n

Il existe de nombreuses interventions th\u00e9rapeutiques pour l’OVR, notamment la th\u00e9rapie au laser, les agents anti-VEGF, les st\u00e9ro\u00efdes et la chirurgie. (6) Dans l’ensemble, les agents anti-VEGF sont aujourd’hui au c\u0153ur du traitement de l’OVR.[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00a0\u00bb4.6.6″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb background_color=\u00a0\u00bbrgba(135,210,150,0.26)\u00a0\u00bb width_tablet=\u00a0\u00bb\u00a0\u00bb width_phone=\u00a0\u00bb90%\u00a0\u00bb width_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_margin=\u00a0\u00bb30px||30px||false|false\u00a0\u00bb border_color_all=\u00a0\u00bb#87d296″ global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb4_4″ _builder_version=\u00a0\u00bb4.6.5″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb custom_padding=\u00a0\u00bb||||false|false\u00a0\u00bb custom_padding_tablet=\u00a0\u00bb|20px||20px|false|false\u00a0\u00bb custom_padding_phone=\u00a0\u00bb|20px||20px|false|false\u00a0\u00bb custom_padding_last_edited=\u00a0\u00bbon|tablet\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.14.5″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb text_font=\u00a0\u00bbMontserrat Regular|500|||||||\u00a0\u00bb text_line_height=\u00a0\u00bb1.25em\u00a0\u00bb quote_font=\u00a0\u00bbMontserrat||||||||\u00a0\u00bb quote_text_align=\u00a0\u00bbleft\u00a0\u00bb quote_font_size=\u00a0\u00bb2rem\u00a0\u00bb quote_line_height=\u00a0\u00bb1.4em\u00a0\u00bb max_width=\u00a0\u00bb782px\u00a0\u00bb module_alignment=\u00a0\u00bbcenter\u00a0\u00bb text_font_size_tablet=\u00a0\u00bb\u00a0\u00bb text_font_size_phone=\u00a0\u00bb1rem\u00a0\u00bb text_font_size_last_edited=\u00a0\u00bbon|tablet\u00a0\u00bb text_line_height_tablet=\u00a0\u00bb\u00a0\u00bb text_line_height_phone=\u00a0\u00bb1.28em\u00a0\u00bb text_line_height_last_edited=\u00a0\u00bbon|tablet\u00a0\u00bb quote_font_size_tablet=\u00a0\u00bb1.5rem\u00a0\u00bb quote_font_size_phone=\u00a0\u00bb1.4rem\u00a0\u00bb quote_font_size_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb quote_line_height_tablet=\u00a0\u00bb\u00a0\u00bb quote_line_height_phone=\u00a0\u00bb\u00a0\u00bb quote_line_height_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

Dans la qu\u00eate de nouveaux biomarqueurs h\u00e9modynamiques, de grands progr\u00e8s ont \u00e9t\u00e9 r\u00e9alis\u00e9s dans la compr\u00e9hension de l’importance du d\u00e9r\u00e8glement de l’oxyg\u00e9nation dans l’OVR.<\/p><\/blockquote>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00a0\u00bb4.6.5″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb width_tablet=\u00a0\u00bb\u00a0\u00bb width_phone=\u00a0\u00bb90%\u00a0\u00bb width_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_margin=\u00a0\u00bb||||false|false\u00a0\u00bb custom_padding=\u00a0\u00bb0px||||false|false\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb4_4″ _builder_version=\u00a0\u00bb4.6.5″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.14.5″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb text_font_size=\u00a0\u00bb1.1rem\u00a0\u00bb text_line_height=\u00a0\u00bb1.6em\u00a0\u00bb header_3_font=\u00a0\u00bbMontserrat|500|||||||\u00a0\u00bb header_3_text_color=\u00a0\u00bb#5a5a5a\u00a0\u00bb header_3_font_size=\u00a0\u00bb1.6rem\u00a0\u00bb header_3_line_height=\u00a0\u00bb1.6em\u00a0\u00bb header_4_font=\u00a0\u00bbMontserrat|600|||on||||\u00a0\u00bb header_4_text_color=\u00a0\u00bb#5A5A5A\u00a0\u00bb header_4_line_height=\u00a0\u00bb2em\u00a0\u00bb max_width=\u00a0\u00bb782px\u00a0\u00bb max_width_tablet=\u00a0\u00bb\u00a0\u00bb max_width_phone=\u00a0\u00bb\u00a0\u00bb max_width_last_edited=\u00a0\u00bbon|desktop\u00a0\u00bb module_alignment=\u00a0\u00bbcenter\u00a0\u00bb custom_margin_tablet=\u00a0\u00bb0vh||||false|false\u00a0\u00bb custom_margin_phone=\u00a0\u00bb0vh||||false|false\u00a0\u00bb custom_margin_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_padding=\u00a0\u00bb||||false|false\u00a0\u00bb text_font_size_tablet=\u00a0\u00bb1.06rem\u00a0\u00bb text_font_size_phone=\u00a0\u00bb1.06rem\u00a0\u00bb header_3_font_size_tablet=\u00a0\u00bb\u00a0\u00bb header_3_font_size_phone=\u00a0\u00bb\u00a0\u00bb header_3_font_size_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb header_4_line_height_tablet=\u00a0\u00bb2em\u00a0\u00bb header_4_line_height_phone=\u00a0\u00bb2em\u00a0\u00bb header_4_line_height_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

Oxym\u00e9trie des vaisseaux r\u00e9tiniens<\/h3>\n

Au cours de la derni\u00e8re d\u00e9cennie, de nombreuses \u00e9tudes utilisant des oxym\u00e8tres traditionnels \u00e0 deux longueurs d’onde ont r\u00e9v\u00e9l\u00e9 que la saturation en oxyg\u00e8ne dans les gros vaisseaux sanguins est affect\u00e9e dans l’OVR. Dans une \u00e9tude normative, la saturation moyenne estim\u00e9e (\u00b1SD) en oxyg\u00e8ne de l’h\u00e9moglobine chez des individus sains \u00e9tait de 92,2 \u00b1 3,7% dans les art\u00e8res et de 55,6 \u00b1 6,3% dans les veines. (11) On a constat\u00e9 que ces valeurs dans les veinules r\u00e9tiniennes des yeux affect\u00e9s par l\u2019OVCR sont significativement plus faibles que celles des yeux non affect\u00e9s. Cela est probablement d\u00fb au fait que l’obstruction vasculaire entra\u00eene une diminution du flux sanguin, et donc une r\u00e9duction de l’apport d’oxyg\u00e8ne aux tissus. Les tissus hypoxiques consomment plus d’oxyg\u00e8ne du sang car le flux vasculaire \u00e0 travers le lit capillaire est diminu\u00e9. En revanche, la saturation art\u00e9riolaire ne diff\u00e8re pas de mani\u00e8re significative entre les yeux affect\u00e9s et les yeux non affect\u00e9s. (8) Ceci est coh\u00e9rent avec la physiopathologie connue de l\u2019OVCR.<\/p>\n

En outre, il a \u00e9t\u00e9 d\u00e9montr\u00e9 qu’il existe des diff\u00e9rences interindividuelles dans les mesures d’oxym\u00e9trie des vaisseaux r\u00e9tiniens dans l’OVR. L’obstruction diff\u00e8re d’un patient \u00e0 l’autre, en raison de divers m\u00e9canismes compensatoires initi\u00e9s par l’occlusion veineuse. La canalisation progressive du thrombus, ainsi que le d\u00e9veloppement de vaisseaux collat\u00e9raux, contribuent \u00e9galement \u00e0 cette variabilit\u00e9. (11) Les recherches sugg\u00e8rent \u00e9galement que, lors du diagnostic, la saturation en oxyg\u00e8ne des veinules r\u00e9tiniennes serait corr\u00e9l\u00e9e avec l’acuit\u00e9 visuelle corrig\u00e9e du meilleur \u0153il.<\/p>\n

Nouvelle approche de l’oxym\u00e9trie oculaire<\/h3>\n

Si les \u00e9tudes susmentionn\u00e9es ont jou\u00e9 un grand r\u00f4le dans l’\u00e9tablissement du lien entre l’oxyg\u00e9nation des vaisseaux r\u00e9tiniens et l’OVR, elles comportent \u00e9galement d’importantes limitations dues aux technologies utilis\u00e9es pour effectuer les mesures. En effet, les appareils d’oxym\u00e9trie standard \u00e0 deux longueurs d’onde ne fournissent que des mesures relatives de saturation en oxyg\u00e8ne dans les gros vaisseaux sanguins du fond de l\u2019\u0153il. Cette limitation emp\u00eache l\u2019\u00e9valuation de tissus sp\u00e9cifiques tels que la r\u00e9tine ou la t\u00eate du nerf optique.<\/p>\n

Pour devenir cliniquement pertinentes, les mesures d’oxym\u00e9trie doivent devenir fiables, reproductibles et s’adapter \u00e0 diff\u00e9rents protocoles d’acquisition, ainsi qu’\u00e0 des mesures statiques et dynamiques \u00e0 diff\u00e9rents endroits du fond de l’\u0153il. C’est pourquoi Zilia a lanc\u00e9 sur le march\u00e9 de la recherche, Zilia Ocular<\/a><\/span><\/span>, la premi\u00e8re cam\u00e9ra r\u00e9tinienne permettant la mesure de la saturation en oxyg\u00e8ne dans des r\u00e9gions cibl\u00e9es de la r\u00e9tine. Cette nouvelle technologie ouvre la voie \u00e0 l’\u00e9tude non invasive de l’oxyg\u00e9nation dans des contextes de r\u00e9ponse m\u00e9tabolique, de processus pathophysiologiques et de suivis th\u00e9rapeutiques.<\/p>\n

Cette nouvelle approche pourrait fournir de nouvelles informations cruciales sur l’\u00e9tat de perfusion de la r\u00e9tine avec le but ultime d’am\u00e9liorer le diagnostic, le pronostic et le suivi du traitement de conditions comme l’OVR.<\/p>\n

Conclusion<\/h3>\n

L’OVR est une cause importante de perte de vision chez les personnes \u00e2g\u00e9es, surtout si l’on consid\u00e8re l’augmentation des taux de maladies pr\u00e9disposantes. Les outils de diagnostic traditionnels reposent sur des mesures invasives pour g\u00e9n\u00e9rer des donn\u00e9es qualitatives sur la perfusion r\u00e9tinienne. Dans la qu\u00eate de nouveaux biomarqueurs h\u00e9modynamiques, de grands progr\u00e8s ont \u00e9t\u00e9 r\u00e9alis\u00e9s dans la compr\u00e9hension de l’importance du d\u00e9r\u00e8glement de l’oxyg\u00e9nation dans l’OVR. Cependant, l’abondance des recherches effectu\u00e9es \u00e0 l’aide d’oxym\u00e8tres de vaisseaux r\u00e9tiniens ne s’est pas encore traduite par le d\u00e9ploiement de ces technologies en milieu clinique, principalement en raison d’un manque de pr\u00e9cision et de polyvalence. S’appuyant sur le spectre complet de la lumi\u00e8re, la technologie de Zilia a le potentiel de surmonter ces limitations en recueillant des donn\u00e9es quantitatives d’oxym\u00e9trie oculaire dans les tissus de l’\u0153il, de mani\u00e8re non invasive, dans le but de permettre une meilleure prise en charge de l’OVR.<\/p>\n

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R\u00e9f\u00e9rences<\/h3>\n

1. Klein R, Klein Be, Moss Se, Meuer Sm. The epidemiology of retinal vein occlusion: The beaver dam eye study. Trans Am Ophthalmol Soc. 98, 133-141; discussion 141-133 (2000).<\/p>\n

2. Blair K, Czyz CN. Central Retinal Vein Occlusion. In: StatPearls. StatPearls Publishing, Treasure Island (FL); 2021. PMID: 30252241.<\/p>\n

3. Ehlken C, Rennel E, Michels D et al. Levels of VEGF but not VEGF165b are Increased in the Vitreous of Patients With Retinal Vein Occlusion. Am J Ophthalmol. 2011;152 (2):298-303.e1. doi:10.1016\/j.ajo.2011.01.040<\/p>\n

4. Thapa R, Bajimaya S, Paudyal G et al. Prevalence, pattern and risk factors of retinal vein occlusion in an elderly population in Nepal: the Bhaktapur retina study. BMC Ophthalmol. 2017;17(1). doi:10.1186\/s12886-017-0552-x<\/p>\n

5. Song P, Xu Y, Zha M, Zhang Y, Rudan I. Global epidemiology of retinal vein occlusion: a systematic review and meta-analysis of prevalence, incidence, and risk factors. J Glob Health. 2019;9(1):010427. doi:10.7189\/jogh.09.010427<\/p>\n

6. Seknazi D, Coscas F, Sellam A, Rouimi F, Coscas G, Souied E, Glaget-Bernard A. Optical Coherence Tomography Angiography in Retinal Vein Occlusion. Retina. 2018;38(1):1562\u20131570. doi: 10.1097\/IAE.0000000000001737<\/p>\n

7. Schmidt-Erfurth U, Garcia-Arumi J, Gerendas B et al. Guidelines for the Management of Retinal Vein Occlusion by the European Society of Retina Specialists (EURETINA). Ophthalmologica. 2019;242 (3):123\u2013162. doi:10.1159\/000502041<\/p>\n

8. Hardarson SH, Stef\u00e1nsson E. Oxygen saturation in central retinal vein occlusion. American journal of ophthalmology. 2010;150 (6):871-5. doi: 10.1016\/j.ajo.2010.06.020<\/p>\n

9. Krejberg Jeppesen S, S\u00edn M, Hakon Hardarson S, Bek T. Retinal oximetry does not predict 12-month visual outcome after anti-VEGF treatment for central retinal vein occlusion: A multicentre study. Acta Ophthalmol. 2021;99(7): e1141-e1145. doi:10.1111\/aos.14744<\/p>\n

10. Yoneya, S, Saito, T, Nishiyama, Y, Deguchi, T, Takasu, M, Gil, T, & Horn, E. Retinal oxygen saturation levels in patients with central retinal vein occlusion. Ophthalmology. 2002;109 (8):1521\u20131526. doi: 10.1016\/S0161-6420 (02)01109-0<\/p>\n

11. \u0160\u00ednov\u00e1 I, \u0158eh\u00e1k J, Nekolov\u00e1 J, Jir\u00e1skov\u00e1 NA, Haluzov\u00e1 P, \u0158eh\u00e1kov\u00e1 T, B\u00e1bkov\u00e1 B, Hejsek L, \u0160\u00edn M. Correlation between ischemic index of retinal vein occlusion and oxygen saturation in retinal vessels. American Journal of Ophthalmology. 2018;188:74-80.<\/p>\n

12. Tsai G, Banaee T, Conti FF, Singh RP. Optical Coherence Tomography Angiography in Eyes with Retinal Vein Occlusion. J Ophthalmic Vis Res. 2018;13(3):315\u2013332. doi:10.4103\/jovr.jovr_264_17<\/p>\n

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Lecture additionnelle<\/h2>\n

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\u00c0 propos<\/p>\n

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Zilia Inc. \u00a9 2020 <\/p>\n

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Zilia Inc. \u00a9 2021<\/p>\n

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L’occlusion veineuse r\u00e9tinienne (OVR) touche plus de 1,1 million de personnes aux \u00c9tats-Unis et est consid\u00e9r\u00e9e comme l\u2019une des principales causes de perte de vision chez les personnes \u00e2g\u00e9es. (1)Il existe deux types d\u2019OVR selon la localisation de l’obstruction: occlusion de la veine centrale de la r\u00e9tine (OVCR) et occlusion d\u2019une branche veineuse de la […]<\/p>\n","protected":false},"author":3,"featured_media":237458,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"2880","content-type":"","inline_featured_image":false,"footnotes":""},"categories":[17],"tags":[70,176,147],"class_list":["post-237468","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-non-classifiee","tag-oxymetrie-oculaire","tag-retinal-vein-occlusion-fr","tag-ziliaocular-fr"],"yoast_head":"\nOxym\u00e9trie oculaire : Un changement de paradigme dans la gestion des occlusions veineuses r\u00e9tiniennes? - Zilia<\/title>\n<meta name=\"description\" content=\"De grands progr\u00e8s ont \u00e9t\u00e9 r\u00e9alis\u00e9s dans la compr\u00e9hension de l'importance du d\u00e9r\u00e8glement de l'oxyg\u00e9nation dans l'OVR.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/ziliahealth.com\/fr\/blog\/oxymetrie-oculaire-changement-paradigme-gestion-occlusions-veineuses-retiniennes\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Oxym\u00e9trie oculaire : Un changement de paradigme dans la gestion des occlusions veineuses r\u00e9tiniennes? - 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