{"id":238666,"date":"2024-12-03T09:46:56","date_gmt":"2024-12-03T14:46:56","guid":{"rendered":"https:\/\/ziliahealth.com\/blog\/oculomics-non-invasive-health-insights\/"},"modified":"2024-12-03T11:24:04","modified_gmt":"2024-12-03T16:24:04","slug":"oculomique-regard-noninvasif-sante-globale","status":"publish","type":"post","link":"https:\/\/ziliahealth.com\/fr\/blog\/oculomique-regard-noninvasif-sante-globale\/","title":{"rendered":"Oculomique: Un regard non-invasif sur la sant\u00e9 globale"},"content":{"rendered":"

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sur la sant\u00e9 globale\u00a0\u00bb button_url=\u00a0\u00bbhttps:\/\/jhvs2020.jp\/en\/\u00a0\u00bb url_new_window=\u00a0\u00bbon\u00a0\u00bb admin_label=\u00a0\u00bbTitle Paragraph & CTA Button\u00a0\u00bb _builder_version=\u00a0\u00bb4.27.4″ header_font=\u00a0\u00bbMontserrat|500|||||||\u00a0\u00bb header_text_color=\u00a0\u00bb#5A5A5A\u00a0\u00bb header_font_size=\u00a0\u00bb3rem\u00a0\u00bb header_line_height=\u00a0\u00bb1.2em\u00a0\u00bb body_font=\u00a0\u00bbMontserrat Regular||||||||\u00a0\u00bb body_text_color=\u00a0\u00bb#5A5A5A\u00a0\u00bb body_font_size=\u00a0\u00bb1.1rem\u00a0\u00bb body_line_height=\u00a0\u00bb1.6em\u00a0\u00bb use_background_color=\u00a0\u00bboff\u00a0\u00bb custom_button=\u00a0\u00bbon\u00a0\u00bb button_text_size=\u00a0\u00bb1rem\u00a0\u00bb button_text_color=\u00a0\u00bb#5a5a5a\u00a0\u00bb button_border_width=\u00a0\u00bb0px\u00a0\u00bb button_border_color=\u00a0\u00bbrgba(0,0,0,0)\u00a0\u00bb button_border_radius=\u00a0\u00bb0px\u00a0\u00bb 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button_one_letter_spacing__hover_enabled=\u00a0\u00bboff\u00a0\u00bb button_two_letter_spacing__hover_enabled=\u00a0\u00bboff\u00a0\u00bb button_bg_color__hover_enabled=\u00a0\u00bboff\u00a0\u00bb button_one_bg_color__hover_enabled=\u00a0\u00bboff\u00a0\u00bb button_two_bg_color__hover_enabled=\u00a0\u00bboff\u00a0\u00bb header_2_font_size_tablet=\u00a0\u00bb2.1rem\u00a0\u00bb header_2_font_size_phone=\u00a0\u00bb1.6rem\u00a0\u00bb header_2_font_size_last_edited=\u00a0\u00bbon|desktop\u00a0\u00bb header_2_line_height_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb header_3_font_size_tablet=\u00a0\u00bb1.7rem\u00a0\u00bb header_3_font_size_phone=\u00a0\u00bb1.5rem\u00a0\u00bb header_3_font_size_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb header_3_line_height_tablet=\u00a0\u00bb1.3em\u00a0\u00bb header_3_line_height_phone=\u00a0\u00bb1.4em\u00a0\u00bb header_3_line_height_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_css_promo_title_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb 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On dit souvent que les yeux sont le miroir de l’\u00e2me, mais ils refl\u00e8tent tout autant notre sant\u00e9. Les caract\u00e9ristiques anatomiques uniques de l’\u0153il lui permettent non seulement d’assurer des fonctions visuelles essentielles, mais aussi de constituer une fen\u00eatre pr\u00e9cieuse pour la d\u00e9tection pr\u00e9coce de maladies syst\u00e9miques. Cette capacit\u00e9 est renforc\u00e9e par l\u2019accessibilit\u00e9 de l\u2019\u0153il aux technologies d\u2019imagerie non invasives, capables d\u2019examiner son r\u00e9seau complexe de vaisseaux sanguins et son nerf optique, r\u00e9v\u00e9lant souvent des signes de maladie avant m\u00eame l\u2019apparition des sympt\u00f4mes. De plus, l\u2019int\u00e9gration de technologies innovantes, souvent aliment\u00e9es par l\u2019intelligence artificielle (IA), marque un tournant d\u00e9cisif en donnant aux professionnels les moyens de d\u00e9tecter une large gamme de maladies non oculaires lors d\u2019examens de la vue.<\/span><\/p>\n

Avec l\u2019essor de ces nouvelles technologies dans les milieux cliniques, les examens de la vue sont en passe de devenir des opportunit\u00e9s incontournables pour d\u00e9tecter les probl\u00e8mes de sant\u00e9 d\u00e8s leurs premiers stades. Accessibles et \u00e9conomiques, ces outils transforment de plus en plus les examens de la vue en une composante essentielle des soins pr\u00e9ventifs, favorisant des traitements m\u00e9dicaux plus personnalis\u00e9s.<\/span><\/p>\n

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Comprendre l\u2019oculome et l\u2019oculomique<\/h3>\n

Les changements observables dans l’\u0153il, qu’ils soient microscopiques ou visibles \u00e0 l’\u0153il nu, constituent ce qu’on appelle l\u2019\u00ab oculome \u00bb. Au c\u0153ur de ce concept se trouve l\u2019identification de biomarqueurs oculaires \u2013 des indicateurs objectifs permettant de pr\u00e9dire, d\u2019\u00e9valuer ou de diagnostiquer des maladies, tout en orientant les choix th\u00e9rapeutiques. L’\u00e9tude de ces biomarqueurs, ainsi que des autres modifications oculaires et de leur lien avec la sant\u00e9 syst\u00e9mique, rel\u00e8ve d\u2019un domaine \u00e9mergent appel\u00e9 \u00ab oculomique \u00bb. (1) Cette discipline exploite les donn\u00e9es issues des examens de la vue, de l\u2019imagerie et des tests diagnostiques pour identifier et surveiller des maladies syst\u00e9miques, \u00e9valuer les risques et mesurer les r\u00e9ponses aux traitements.<\/p>\n

L\u2019\u0153il est d\u2019ailleurs unique : c\u2019est le seul endroit du corps humain o\u00f9 les tissus nerveux et les vaisseaux sanguins peuvent \u00eatre observ\u00e9s directement et sans obstruction. Cet acc\u00e8s privil\u00e9gi\u00e9 \u00e0 la r\u00e9tine et \u00e0 son syst\u00e8me circulatoire complexe permet d\u2019\u00e9valuer l\u2019int\u00e9grit\u00e9 des structures et de d\u00e9tecter, ainsi que de quantifier, un large \u00e9ventail de prot\u00e9ines et de mol\u00e9cules circulant dans le sang. Ces observations peuvent r\u00e9v\u00e9ler des signes pr\u00e9coces de nombreuses maladies, notamment des troubles neurod\u00e9g\u00e9n\u00e9ratifs, psychiatriques, cardiovasculaires, h\u00e9matologiques, respiratoires, auto-immuns, ainsi que certains cancers ou toxicit\u00e9s m\u00e9dicamenteuses. (2)<\/p>\n

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Le r\u00f4le de l’\u0153il dans la d\u00e9tection des maladies non oculaires<\/h3>\n

L\u2019efficacit\u00e9 de l\u2019oculomique est d\u00e9j\u00e0 bien document\u00e9e dans la litt\u00e9rature m\u00e9dicale, avec de nombreux exemples montrant comment des examens de la vue de routine permettent aujourd\u2019hui d\u2019obtenir des informations pr\u00e9cieuses sur la sant\u00e9. Par exemple, la r\u00e9tinopathie diab\u00e9tique, une complication du diab\u00e8te, est souvent identifi\u00e9e gr\u00e2ce \u00e0 l\u2019observation de modifications dans les vaisseaux sanguins de la r\u00e9tine, comme des microan\u00e9vrismes, des h\u00e9morragies ou des fuites de liquide. Ces signes r\u00e9v\u00e8lent un m\u00e9tabolisme du glucose perturb\u00e9, parfois avant m\u00eame l\u2019apparition d\u2019autres sympt\u00f4mes syst\u00e9miques. (3) De m\u00eame, l\u2019\u00e9tat des vaisseaux r\u00e9tiniens fournit des indications cruciales sur la sant\u00e9 cardiovasculaire. Des signes tels que le r\u00e9tr\u00e9cissement, la tortuosit\u00e9 ou la pr\u00e9sence d\u2019h\u00e9morragies r\u00e9tiniennes peuvent r\u00e9v\u00e9ler des probl\u00e8mes sous-jacents comme l\u2019hypertension ou l\u2019ath\u00e9roscl\u00e9rose, signalant potentiellement un risque accru de maladie cardiaque ou d\u2019AVC. (1,4) Par ailleurs, la connexion directe de l’\u0153il au syst\u00e8me nerveux central en fait un outil cl\u00e9 pour identifier les maladies neurologiques. Par exemple, la scl\u00e9rose en plaques, caract\u00e9ris\u00e9e par une inflammation et des l\u00e9sions nerveuses dans le cerveau, se manifeste souvent initialement par une n\u00e9vrite optique \u2013 une inflammation du nerf optique provoquant une perte de vision douloureuse d\u2019un \u0153il, qui peut \u00eatre un indicateur pr\u00e9coce de la maladie. (5)<\/p>\n

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L’oculomique exploite les donn\u00e9es issues des examens de la vue, de l\u2019imagerie et des tests diagnostiques pour identifier et surveiller des maladies syst\u00e9miques, \u00e9valuer les risques et mesurer les r\u00e9ponses aux traitements.<\/p><\/blockquote>\n

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Avec l\u2019av\u00e8nement de l\u2019IA, le potentiel de l\u2019oculomique s\u2019est consid\u00e9rablement accru, ouvrant des perspectives autrefois inimaginables et amor\u00e7ant des r\u00e9volutions \u00e0 venir. Voici un aper\u00e7u des avanc\u00e9es les plus prometteuses :<\/p>\n

Troubles neurod\u00e9g\u00e9n\u00e9ratifs et psychiatriques<\/h4>\n

Maladie de Parkinson:<\/strong> Les technologies d\u2019eye-tracking pilot\u00e9es par l\u2019IA et l\u2019imagerie hyperspectrale de la r\u00e9tine s\u2019imposent comme des outils prometteurs pour la d\u00e9tection pr\u00e9coce de cette maladie. L\u2019eye-tracking peut capturer des alt\u00e9rations subtiles des mouvements oculaires, tandis que l\u2019imagerie hyperspectrale analyse la composition biochimique de l\u2019\u0153il pour identifier des anomalies sp\u00e9cifiques. (6-7)<\/p>\n

Maladie d\u2019Alzheimer:<\/strong> L\u2019imagerie hyperspectrale offre \u00e9galement un potentiel significatif pour la d\u00e9tection pr\u00e9coce de la maladie d\u2019Alzheimer en identifiant de subtiles modifications des tissus r\u00e9tiniens, notamment la pr\u00e9sence de plaques b\u00eata-amylo\u00efdes associ\u00e9es aux processus neurod\u00e9g\u00e9n\u00e9ratifs. (8)
Sant\u00e9 mentale: L\u2019\u00e9lectror\u00e9tinographie (ERG) semble \u00eatre un indicateur prometteur des troubles psychiatriques comme la d\u00e9pression ou la schizophr\u00e9nie. (9-10)<\/p>\n

TDAH et autisme:<\/strong> Les technologies d\u2019eye-tracking bas\u00e9es sur l\u2019IA sont en cours de d\u00e9veloppement pour d\u00e9pister les sympt\u00f4mes du TDAH (11) et de l\u2019autisme (12) chez les enfants.<\/p>\n

Conditions cardiovasculaires et syst\u00e9miques<\/h4>\n

Amylo\u00efdose cardiaque :<\/strong> La spectroscopie oculaire et un nouveau traceur oculaire fluorescent sont deux techniques actuellement \u00e9tudi\u00e9es pour leur capacit\u00e9 \u00e0 d\u00e9tecter l\u2019amylo\u00efdose transthyr\u00e9tine (ATTR), une maladie cardiaque rare mais grave. (13-14)<\/p>\n

Ict\u00e8re et dysfonction h\u00e9patique :<\/strong> L\u2019imagerie optique trans-conjonctive, associ\u00e9e \u00e0 des algorithmes inspir\u00e9s du cerveau humain, est explor\u00e9e comme outil pour identifier et quantifier l\u2019ict\u00e8re, offrant ainsi une possibilit\u00e9 de diagnostic pr\u00e9coce des maladies h\u00e9patiques. (15)<\/p>\n

Pr\u00e9diction de la sarcop\u00e9nie :<\/strong> Les approches bas\u00e9es sur l\u2019apprentissage machine appliqu\u00e9es \u00e0 l\u2019oculomique permettent de pr\u00e9dire la sarcop\u00e9nie, une perte de masse musculaire li\u00e9e \u00e0 l\u2019\u00e2ge, en analysant des images r\u00e9tiniennes pour \u00e9valuer les risques de perte musculaire et les complications associ\u00e9es. (16)<\/p>\n

Cancer<\/h4>\n

Cancer du sein :<\/strong> Une \u00e9tude r\u00e9cente a identifi\u00e9 plusieurs prot\u00e9ines pr\u00e9sentes dans les larmes comme biomarqueurs potentiels pour le d\u00e9pistage non invasif du cancer du sein. (18)<\/p>\n

Cancers de la prostate, du c\u00f4lon, des poumons et des ovaires :<\/strong> Les niveaux de lacryglobine dans les larmes diff\u00e8rent selon les types de cancers. Par exemple, ils sont plus \u00e9lev\u00e9s chez les patients atteints de cancers du c\u00f4lon, de la prostate et des poumons, alors qu\u2019ils sont r\u00e9duits chez ceux atteints d\u2019un cancer des ovaires. (19)<\/p>\n

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Spectroscopie: un outil r\u00e9volutionnaire pour la d\u00e9tection de biomarqueurs<\/h3>\n

La spectroscopie, une technique qui analyse l\u2019interaction entre la lumi\u00e8re et la mati\u00e8re, occupe une place de plus en plus importante dans l’investigation des maladies oculaires et syst\u00e9miques. Bien qu\u2019elle soit d\u00e9j\u00e0 largement utilis\u00e9e en astronomie ou en sciences environnementales, son application \u00e0 l\u2019\u0153il ouvre une nouvelle \u00e8re d\u2019innovation m\u00e9dicale.<\/p>\n

En d\u00e9codant les signatures spectrales uniques des prot\u00e9ines et mol\u00e9cules \u2013 comparables \u00e0 des empreintes digitales mol\u00e9culaires \u2013 la spectroscopie permet une identification et une quantification pr\u00e9cises d\u2019une multitude de biomarqueurs. Cette technologie trouve des applications prometteuses en ophtalmologie, en neurologie, en cardiologie, en soins primaires, et au-del\u00e0.<\/p>\n

Ce qui rend cette innovation particuli\u00e8rement captivante, c\u2019est sa capacit\u00e9 \u00e0 fournir des r\u00e9sultats explicables. En d\u00e9voilant les changements mol\u00e9culaires sp\u00e9cifiques dans l\u2019\u0153il, elle offre une compr\u00e9hension approfondie des processus biologiques en cours. Cette transparence favorise des interventions m\u00e9dicales plus cibl\u00e9es et personnalis\u00e9es.<\/p>\n

L\u2019impact de l\u2019oculomique sur les soins de sant\u00e9<\/h3>\n

En exploitant les capacit\u00e9s diagnostiques uniques de l\u2019\u0153il, l\u2019oculomique promet de transformer l\u2019ensemble du secteur de la sant\u00e9, notamment dans les domaines suivants :<\/span><\/p>\n

D\u00e9tection opportuniste<\/b> : L\u2019oculomique permet aux professionnels de la sant\u00e9 de tirer parti des examens de la vue de routine pour d\u00e9tecter des changements subtils signalant des probl\u00e8mes de sant\u00e9 sous-jacents. Cette approche proactive, souvent qualifi\u00e9e de \u00ab d\u00e9couvertes opportunistes \u00bb, \u00e9tend la port\u00e9e diagnostique des soins ophtalmiques, en faisant de ces examens une passerelle pr\u00e9cieuse pour des interventions pr\u00e9coces.<\/span><\/p>\n

Accessibilit\u00e9 accrue<\/b> : Gr\u00e2ce \u00e0 la proximit\u00e9 des cliniques ophtalmiques, souvent situ\u00e9es dans des centres commerciaux ou des quartiers locaux, les efforts de d\u00e9tection pr\u00e9coce deviennent accessibles \u00e0 une population vari\u00e9e. Combin\u00e9e \u00e0 des tests en temps r\u00e9el, cette approche facilite des \u00e9valuations rapides, \u00e9largissant ainsi l\u2019impact des examens oculaires sur la sant\u00e9 globale.<\/span><\/p>\n

Diagnostics rentables<\/b> : Compar\u00e9e \u00e0 des technologies co\u00fbteuses comme l\u2019IRM ou le scanner, l\u2019oculomique offre une alternative abordable. En d\u00e9mocratisant ces diagnostics avanc\u00e9s, elle contribue \u00e0 am\u00e9liorer les soins individuels tout en r\u00e9duisant les co\u00fbts pour les syst\u00e8mes de sant\u00e9 en limitant les traitements on\u00e9reux ou les hospitalisations.<\/span><\/p>\n

Collaboration interdisciplinaire<\/b> : L\u2019oculomique illustre l\u2019importance d\u2019une collaboration entre disciplines m\u00e9dicales. Lorsqu\u2019une maladie syst\u00e9mique est d\u00e9tect\u00e9e lors d\u2019un examen oculaire, une orientation vers des sp\u00e9cialistes permet d\u2019assurer des soins complets. Cette approche coordonn\u00e9e am\u00e9liore non seulement les r\u00e9sultats pour les patients, mais renforce \u00e9galement l\u2019efficacit\u00e9 du syst\u00e8me de sant\u00e9.<\/span><\/p>\n

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\n

La spectroscopie occupe une place de plus en plus importante dans les diagnostics des maladies oculaires et syst\u00e9miques.<\/p>\n<\/blockquote>\n

[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00a0\u00bb4.16″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb width_tablet=\u00a0\u00bb\u00a0\u00bb width_phone=\u00a0\u00bb90%\u00a0\u00bb width_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_margin=\u00a0\u00bb||||false|false\u00a0\u00bb custom_padding=\u00a0\u00bb0px||||false|false\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb4_4″ _builder_version=\u00a0\u00bb4.16″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_text _builder_version=\u00a0\u00bb4.27.4″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb text_font_size=\u00a0\u00bb1.1rem\u00a0\u00bb text_line_height=\u00a0\u00bb1.6em\u00a0\u00bb header_3_font=\u00a0\u00bbMontserrat|500|||||||\u00a0\u00bb header_3_text_color=\u00a0\u00bb#5a5a5a\u00a0\u00bb header_3_font_size=\u00a0\u00bb1.6rem\u00a0\u00bb header_3_line_height=\u00a0\u00bb1.6em\u00a0\u00bb header_4_font=\u00a0\u00bbMontserrat|600|||on||||\u00a0\u00bb header_4_text_color=\u00a0\u00bb#5A5A5A\u00a0\u00bb header_4_line_height=\u00a0\u00bb2em\u00a0\u00bb max_width=\u00a0\u00bb782px\u00a0\u00bb max_width_tablet=\u00a0\u00bb\u00a0\u00bb max_width_phone=\u00a0\u00bb\u00a0\u00bb max_width_last_edited=\u00a0\u00bbon|desktop\u00a0\u00bb module_alignment=\u00a0\u00bbcenter\u00a0\u00bb custom_margin_tablet=\u00a0\u00bb0vh||||false|false\u00a0\u00bb custom_margin_phone=\u00a0\u00bb0vh||||false|false\u00a0\u00bb custom_margin_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_padding=\u00a0\u00bb||||false|false\u00a0\u00bb text_font_size_tablet=\u00a0\u00bb1.06rem\u00a0\u00bb text_font_size_phone=\u00a0\u00bb1.06rem\u00a0\u00bb header_3_font_size_tablet=\u00a0\u00bb\u00a0\u00bb header_3_font_size_phone=\u00a0\u00bb\u00a0\u00bb header_3_font_size_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb header_4_line_height_tablet=\u00a0\u00bb2em\u00a0\u00bb header_4_line_height_phone=\u00a0\u00bb2em\u00a0\u00bb header_4_line_height_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

Un avenir ax\u00e9 sur la d\u00e9tection pr\u00e9coce et de meilleurs r\u00e9sultats<\/h3>\n

Les avanc\u00e9es en oculomique transforment les examens de la vue de routine en outils puissants pour lutter contre les \u00ab Quatre Cavaliers \u00bb des maladies chroniques modernes : les maladies cardiovasculaires, les cancers, les troubles neurod\u00e9g\u00e9n\u00e9ratifs et les conditions m\u00e9taboliques. En s\u2019appuyant sur des technologies de pointe comme l\u2019imagerie avanc\u00e9e et l\u2019IA, l\u2019oculomique est en mesure d\u2019identifier ces ennemis redoutables \u00e0 leurs premiers stades, bien avant qu\u2019ils ne causent des dommages irr\u00e9versibles. Cette approche proactive am\u00e9liore non seulement les r\u00e9sultats pour les patients, mais repr\u00e9sente \u00e9galement un v\u00e9ritable tournant dans la gestion des grands d\u00e9fis de sant\u00e9 de notre \u00e9poque.<\/span><\/p>\n

Au fur et \u00e0 mesure que la recherche progresse, les innovations en d\u00e9tection de biomarqueurs oculaires continuent de remodeler les soins de sant\u00e9. Avec des avanc\u00e9es constantes, notamment gr\u00e2ce \u00e0 des entreprises comme Zilia et sa <\/span>plateforme technologique bas\u00e9e sur la spectroscopie non invasive<\/span><\/span><\/a>, l\u2019\u0153il pourrait bient\u00f4t devenir notre alli\u00e9 le plus pr\u00e9cieux dans la lutte contre ces maladies omnipr\u00e9sentes. Cette perspective ouvre la voie \u00e0 un avenir o\u00f9 la d\u00e9tection pr\u00e9coce et les soins personnalis\u00e9s permettront \u00e0 chacun de vivre plus longtemps et en meilleure sant\u00e9.<\/span>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00a0\u00bb4.16″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb width_tablet=\u00a0\u00bb\u00a0\u00bb width_phone=\u00a0\u00bb90%\u00a0\u00bb width_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_margin=\u00a0\u00bb3em||||false|false\u00a0\u00bb custom_padding=\u00a0\u00bb0px||||false|false\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_column type=\u00a0\u00bb4_4″ _builder_version=\u00a0\u00bb4.16″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][et_pb_divider color=\u00a0\u00bb#87d296″ divider_weight=\u00a0\u00bb1px\u00a0\u00bb _builder_version=\u00a0\u00bb4.16″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb max_width=\u00a0\u00bb782px\u00a0\u00bb module_alignment=\u00a0\u00bbcenter\u00a0\u00bb custom_margin=\u00a0\u00bb3em||0px||false|false\u00a0\u00bb custom_margin_tablet=\u00a0\u00bb3em||0px||false|false\u00a0\u00bb custom_margin_phone=\u00a0\u00bb3em||0px||false|false\u00a0\u00bb custom_margin_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_padding=\u00a0\u00bb||||false|false\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb][\/et_pb_divider][et_pb_text _builder_version=\u00a0\u00bb4.27.4″ _module_preset=\u00a0\u00bbdefault\u00a0\u00bb text_font_size=\u00a0\u00bb1.1rem\u00a0\u00bb text_line_height=\u00a0\u00bb1.6em\u00a0\u00bb header_3_font=\u00a0\u00bbMontserrat|500|||||||\u00a0\u00bb header_3_text_color=\u00a0\u00bb#5a5a5a\u00a0\u00bb header_3_font_size=\u00a0\u00bb1.6rem\u00a0\u00bb header_3_line_height=\u00a0\u00bb1.6em\u00a0\u00bb header_4_font=\u00a0\u00bbMontserrat|600|||on||||\u00a0\u00bb header_4_text_color=\u00a0\u00bb#5A5A5A\u00a0\u00bb header_4_line_height=\u00a0\u00bb1.6em\u00a0\u00bb max_width=\u00a0\u00bb782px\u00a0\u00bb max_width_tablet=\u00a0\u00bb\u00a0\u00bb max_width_phone=\u00a0\u00bb\u00a0\u00bb max_width_last_edited=\u00a0\u00bbon|desktop\u00a0\u00bb module_alignment=\u00a0\u00bbcenter\u00a0\u00bb custom_margin_tablet=\u00a0\u00bb0vh||||false|false\u00a0\u00bb custom_margin_phone=\u00a0\u00bb0vh||||false|false\u00a0\u00bb custom_margin_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb custom_padding=\u00a0\u00bb||||false|false\u00a0\u00bb text_font_size_tablet=\u00a0\u00bb1.06rem\u00a0\u00bb text_font_size_phone=\u00a0\u00bb1.06rem\u00a0\u00bb header_3_font_size_tablet=\u00a0\u00bb\u00a0\u00bb header_3_font_size_phone=\u00a0\u00bb\u00a0\u00bb header_3_font_size_last_edited=\u00a0\u00bbon|phone\u00a0\u00bb border_color_top=\u00a0\u00bb#cccccc\u00a0\u00bb global_colors_info=\u00a0\u00bb{}\u00a0\u00bb]<\/p>\n

R\u00e9f\u00e9rences<\/h3>\n
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  19. Nandi SK, Singh D, Upadhay J, Gupta N, Dhiman N, Mittal SK, Mahindroo N. Identification of tear-based protein and non-protein biomarkers: Its application in diagnosis of human diseases using biosensors. <\/span>Int J Biol Macromol.<\/span><\/i> 2021;193(Part A):838-846.<\/span> <\/a>https:\/\/doi.org\/10.1016\/j.ijbiomac.2021.10.198<\/a><\/a><\/span><\/li>\n
  20. Lapointe N, Akitegetse C, Poirier J, Picard M, Sauvageau P, Sauvageau D. Targeted spectroscopy in the eye fundus. J Biomed Opt<\/i>. 2023 Dec;28(12):126004. doi: 10.1117\/1.JBO.28.12.126004. Epub 2023 Dec 15. PMID: 38111476; PMCID: PMC10725981.<\/li>\n<\/ol>\n

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    EN<\/a><\/p>\n

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    Zilia Inc. \u00a9 2023<\/p>\n

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    Zilia Inc. \u00a9 2023<\/p>\n

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    Zilia Inc. \u00a9 2024<\/p>\n

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    On dit souvent que les yeux sont le miroir de l’\u00e2me, mais ils refl\u00e8tent tout autant notre sant\u00e9. On dit souvent que les yeux sont le miroir de l’\u00e2me, mais ils refl\u00e8tent tout autant notre sant\u00e9. Les caract\u00e9ristiques anatomiques uniques de l’\u0153il lui permettent non seulement d’assurer des fonctions visuelles essentielles, mais aussi de constituer […]<\/p>\n","protected":false},"author":3,"featured_media":238656,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"2880","content-type":"","inline_featured_image":false,"footnotes":""},"categories":[17],"tags":[240,283,284,282,286,285,276,95],"class_list":["post-238666","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-non-classifiee","tag-biomarqueurs-oculaires","tag-detection-precoce-des-maladies","tag-diagnostics-non-invasifs","tag-intelligence-artificielle-dans-les-soins-de-sante","tag-medecine-personnalisee","tag-oculomique","tag-personalized-medicine","tag-sante-oculaire"],"yoast_head":"\nOculomique: Un regard non-invasif sur la sant\u00e9 globale - 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