Early detection of ocular diseases is paramount to prevent vision loss.
Current clinical tools focus on anatomy and, therefore, assess damages already made to the eye, which often means, too late.
Eye Diseases are on the Rise
The prevalence of the three main causes of avoidable blindness is expected to increase significantly by 2030.
Age-related Macular Degeneration
A Paradigm Shift in Ocular Disease Management
What is Ocular Oximetry?
Ocular oximetry is a non-invasive technique that allows the measurement of oxygen saturation of blood (StO₂) in the eye. A rapidly growing number of studies show that oxygen dysregulation plays a central role in several ocular pathologies such as glaucoma, diabetic retinopathy, and age-related macular degeneration.
How is StO₂ Calculated?
Zilia’s technology uses light to acquire spectral information at a precise location of the eye fundus. A proprietary algorithm then extracts the known absorption spectra of the oxygenated and deoxygenated states of hemoglobin to calculate the effective oxygen saturation (StO₂).
Improving Visual Outcomes
Oxygen saturation is an early biomarker of eye diseases and could help identify issues before irreversible damage occurs.
Having critical information about the eye’s metabolism allows treatment to start earlier.
Unprecedented insights open the door to the development of improved treatments and new drugs.
What Experts Think
“Zilia’s ocular oximetry technology can capture real-time metabolic information of the retina and optic nerve, which has the potential to transform diagnosis and management of retinal diseases.”
Dr. Daniel L. Chao, M.D., Ph.D
Assistant Professor of Ophthalmology, UCSD Shiley Eye Institute
Dr Rajat Agrawal, M.D., M.S.
Adjunct Faculty, USC Roski Eye Institute, CEO of Retina Global
“Zilia’s ocular oximetry technology will not only be a valuable tool for eye and vision research but will certainly become an essential means for the early detection of ocular and systemic diseases in clinical settings.”
Dr. Christian Casanova, Ph.D
Dean, School of Optometry, University of Montreal